BDBM50105559 1-Benzyl-5-(3-chloro-phenyl)-1,3-dihydro-benzoimidazol-2-one::CHEMBL94162

SMILES Clc1cccc(c1)-c1ccc2n(Cc3ccccc3)c(=O)[nH]c2c1

InChI Key InChIKey=JTJWERWUFWISDB-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105559   

TargetProgesterone receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105559(1-Benzyl-5-(3-chloro-phenyl)-1,3-dihydro-benzoimid...)
Affinity DataKi:  3.13E+3nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105559(1-Benzyl-5-(3-chloro-phenyl)-1,3-dihydro-benzoimid...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105559(1-Benzyl-5-(3-chloro-phenyl)-1,3-dihydro-benzoimid...)
Affinity DataIC50:  3.06E+3nMAssay Description:Inhibitory concentration against progesterone induced PRE-luciferase activity in CV-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed