BDBM50105560 1-Isopropyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoimidazol-2-one::CHEMBL327444

SMILES CC(C)n1c2c[c-](ccc2nc1=[OH+])-c1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=ZZJYSWFSESMOQN-UHFFFAOYSA-O

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105560   

TargetProgesterone receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105560(1-Isopropyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoim...)
Affinity DataKi:  525nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105560(1-Isopropyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoim...)
Affinity DataIC50:  73nMAssay Description:Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105560(1-Isopropyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoim...)
Affinity DataIC50:  136nMAssay Description:Inhibitory concentration against progesterone induced PRE-luciferase activity in CV-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed