BDBM50105565 6-(3-Chloro-phenyl)-1-isopropyl-1,3-dihydro-benzoimidazol-2-one::CHEMBL329631

SMILES CC(C)n1c2cc(ccc2[nH]c1=O)-c1cccc(Cl)c1

InChI Key InChIKey=YGGFNZNCDVBJQV-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105565   

TargetProgesterone receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105565(6-(3-Chloro-phenyl)-1-isopropyl-1,3-dihydro-benzoi...)
Affinity DataKi:  525nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105565(6-(3-Chloro-phenyl)-1-isopropyl-1,3-dihydro-benzoi...)
Affinity DataIC50:  113nMAssay Description:Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105565(6-(3-Chloro-phenyl)-1-isopropyl-1,3-dihydro-benzoi...)
Affinity DataIC50:  412nMAssay Description:Inhibitory concentration against progesterone induced PRE-luciferase activity in CV-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105565(6-(3-Chloro-phenyl)-1-isopropyl-1,3-dihydro-benzoi...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed