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BDBM50106183 1-(4-(Hexyloxy)phenyl)-3-(piperidin-1-yl)propan-1-one::1-(4-Hexyloxy-phenyl)-3-piperidin-1-yl-propan-1-one::CHEMBL121893

SMILES: CCCCCCOc1ccc(cc1)C(=O)CCN1CCCCC1

InChI Key: InChIKey=WXYWMSOSIIBMMM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50106183   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv7.1


(Cavia porcellus)
BDBM50106183
PNG
(1-(4-(Hexyloxy)phenyl)-3-(piperidin-1-yl)propan-1-...)
Show SMILES CCCCCCOc1ccc(cc1)C(=O)CCN1CCCCC1
Show InChI InChI=1S/C20H31NO2/c1-2-3-4-8-17-23-19-11-9-18(10-12-19)20(22)13-16-21-14-6-5-7-15-21/h9-12H,2-8,13-17H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes


J Med Chem 44: 3764-7 (2001)


Article DOI: 10.1021/jm015505u
BindingDB Entry DOI: 10.7270/Q2G1604C
More data for this
Ligand-Target Pair
Thyroid hormone receptor


(Homo sapiens (human))
BDBM50106183
PNG
(1-(4-(Hexyloxy)phenyl)-3-(piperidin-1-yl)propan-1-...)
Show SMILES CCCCCCOc1ccc(cc1)C(=O)CCN1CCCCC1
Show InChI InChI=1S/C20H31NO2/c1-2-3-4-8-17-23-19-11-9-18(10-12-19)20(22)13-16-21-14-6-5-7-15-21/h9-12H,2-8,13-17H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 9.20E+3n/an/an/an/an/an/a



St. Jude Children's Hospital

Curated by ChEMBL


Assay Description
Inhibition of SRC2 binding to TRalpha receptor ligand binding domain expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay


J Med Chem 52: 3892-901 (2009)


Article DOI: 10.1021/jm9002704
BindingDB Entry DOI: 10.7270/Q2S75GCS
More data for this
Ligand-Target Pair
Thyroid Hormone Receptor (TR-beta)


(Homo sapiens (human))
BDBM50106183
PNG
(1-(4-(Hexyloxy)phenyl)-3-(piperidin-1-yl)propan-1-...)
Show SMILES CCCCCCOc1ccc(cc1)C(=O)CCN1CCCCC1
Show InChI InChI=1S/C20H31NO2/c1-2-3-4-8-17-23-19-11-9-18(10-12-19)20(22)13-16-21-14-6-5-7-15-21/h9-12H,2-8,13-17H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 9.10E+3n/an/an/an/an/an/a



St. Jude Children's Hospital

Curated by ChEMBL


Assay Description
Inhibition of SRC2 binding to human TRbeta receptor ligand binding domain expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay


J Med Chem 52: 3892-901 (2009)


Article DOI: 10.1021/jm9002704
BindingDB Entry DOI: 10.7270/Q2S75GCS
More data for this
Ligand-Target Pair