BDBM50106517 6-(4-Bromo-thiophen-2-ylmethoxy)-9H-purin-2-ylamine::CHEMBL339133

SMILES Nc1nc(OCc2cc(Br)cs2)c2[nH]cnc2n1

InChI Key InChIKey=JUJPKFNFCWJBCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50106517   

TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50106517(6-(4-Bromo-thiophen-2-ylmethoxy)-9H-purin-2-ylamin...)
Affinity DataIC50:  3nMAssay Description:Inactivation of human O-6-methylguanine-DNA methyltransferase assessed as [3H]methylated protein formation by liquid scintillation counting in presen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50106517(6-(4-Bromo-thiophen-2-ylmethoxy)-9H-purin-2-ylamin...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed