BDBM50106517 6-(4-Bromo-thiophen-2-ylmethoxy)-9H-purin-2-ylamine::CHEMBL339133
SMILES Nc1nc(OCc2cc(Br)cs2)c2[nH]cnc2n1
InChI Key InChIKey=JUJPKFNFCWJBCX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50106517
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Trinity College
Curated by ChEMBL
Trinity College
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inactivation of human O-6-methylguanine-DNA methyltransferase assessed as [3H]methylated protein formation by liquid scintillation counting in presen...More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Trinity College
Curated by ChEMBL
Trinity College
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair