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BDBM50107377 CHEMBL3601469

SMILES: C1CN(CCO1)c1nc(nn2cccc12)-c1ccnc2[nH]ccc12

InChI Key: InChIKey=JTNADXJHKVBEBJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107377   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50107377
PNG
(CHEMBL3601469)
Show SMILES C1CN(CCO1)c1nc(nn2cccc12)-c1ccnc2[nH]ccc12
Show InChI InChI=1S/C17H16N6O/c1-2-14-17(22-8-10-24-11-9-22)20-16(21-23(14)7-1)13-4-6-19-15-12(13)3-5-18-15/h1-7H,8-11H2,(H,18,19)
PDB
MMDB

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Reactome pathway
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 330n/an/an/an/an/an/a



Sphaera Pharma Pte. Ltd

Curated by ChEMBL


Assay Description
Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assay


Bioorg Med Chem Lett 25: 3142-6 (2015)


Article DOI: 10.1016/j.bmcl.2015.06.007
BindingDB Entry DOI: 10.7270/Q2JQ12SB
More data for this
Ligand-Target Pair