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BDBM50107384 CHEMBL3601895

SMILES: COCc1ccc2c(nc(nn12)-c1cnc(N)nc1)N1CCOC[C@@H]1C

InChI Key: InChIKey=KQAFWWHWJXAIMV-NSHDSACASA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107384   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50107384
PNG
(CHEMBL3601895)
Show SMILES COCc1ccc2c(nc(nn12)-c1cnc(N)nc1)N1CCOC[C@@H]1C
Show InChI InChI=1S/C17H21N7O2/c1-11-9-26-6-5-23(11)16-14-4-3-13(10-25-2)24(14)22-15(21-16)12-7-19-17(18)20-8-12/h3-4,7-8,11H,5-6,9-10H2,1-2H3,(H2,18,19,20)/t11-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 90n/an/an/an/an/an/a



Sphaera Pharma Pte. Ltd

Curated by ChEMBL


Assay Description
Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assay


Bioorg Med Chem Lett 25: 3142-6 (2015)


Article DOI: 10.1016/j.bmcl.2015.06.007
BindingDB Entry DOI: 10.7270/Q2JQ12SB
More data for this
Ligand-Target Pair