BDBM50107585 CHEMBL3601908

SMILES Cc1ccc(Nc2ncc(cc2Cl)[C@H](NC(=O)c2nccs2)C2CCCC2)cn1

InChI Key InChIKey=FNGGVFCXCCMXGS-GOSISDBHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107585   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107585(CHEMBL3601908)
Affinity DataIC50:  17nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed