BDBM50107635 CHEMBL140794::N-Cyanomethyl-3-phenyl-2-phenylacetylamino-propionamide

SMILES O=C(Cc1ccccc1)N[C@@H](Cc1ccccc1)C(=O)NCC#N

InChI Key InChIKey=SZYIRUNDFQOSET-KRWDZBQOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50107635   

TargetCathepsin S(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107635(CHEMBL140794 | N-Cyanomethyl-3-phenyl-2-phenylacet...)
Affinity DataIC50:  226nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin S (cat S) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107635(CHEMBL140794 | N-Cyanomethyl-3-phenyl-2-phenylacet...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107635(CHEMBL140794 | N-Cyanomethyl-3-phenyl-2-phenylacet...)
Affinity DataIC50:  170nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin L (cat L) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed