BDBM50107773 4'-Chloro-6-methyl-biphenyl-2-carboxylic acid (7-methanesulfonylamino-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-amide::CHEMBL141014

SMILES Cc1cccc(C(=O)Nc2ccc3CCC(CCc3c2)NS(C)(=O)=O)c1-c1ccc(Cl)cc1

InChI Key InChIKey=CHLMMQSHPOCAPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107773   

TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107773(4'-Chloro-6-methyl-biphenyl-2-carboxylic acid (7-m...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibitory activity against MTP using MTP transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApolipoprotein B-100(Homo sapiens (Human))
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107773(4'-Chloro-6-methyl-biphenyl-2-carboxylic acid (7-m...)
Affinity DataIC50:  5nMAssay Description:Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed