BDBM50108144 CHEMBL75154::N-[1-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-ylmethyl)-2-(4'-trifluoromethyl-biphenyl-4-sulfonyl)-ethyl]-N-hydroxy-formamide

SMILES CC1(C)NC(=O)N(CC(CS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)C(F)(F)F)N(O)C=O)C1=O

InChI Key InChIKey=BYBOLCACCXBYNF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108144   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108144(CHEMBL75154 | N-[1-(4,4-Dimethyl-2,5-dioxo-imidazo...)
Affinity DataIC50:  10nMAssay Description:In vitro selective inhibition against Matrix metalloprotease-9 (MMP-9) using fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108144(CHEMBL75154 | N-[1-(4,4-Dimethyl-2,5-dioxo-imidazo...)
Affinity DataIC50:  44nMAssay Description:In vitro selective inhibition against matrix metalloprotease-1 (MMP-1) using a fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108144(CHEMBL75154 | N-[1-(4,4-Dimethyl-2,5-dioxo-imidazo...)
Affinity DataIC50:  0.450nMAssay Description:In vitro selective inhibition against matrix metalloprotease-2 (MMP-2) using fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed