BDBM50108157 CHEMBL75139::N-[2-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-(3,4,4-trimethyl-2,5-dioxo-imidazolidin-1-ylmethyl)-ethyl]-N-hydroxy-formamide

SMILES CN1C(=O)N(CC(CS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)N(O)C=O)C(=O)C1(C)C

InChI Key InChIKey=SBVGWUXDJBPGDG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108157   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108157(CHEMBL75139 | N-[2-[4-(4-Chloro-phenoxy)-benzenesu...)
Affinity DataIC50:  1.40nMAssay Description:In vitro selective inhibition against Matrix metalloprotease-9 (MMP-9) using fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108157(CHEMBL75139 | N-[2-[4-(4-Chloro-phenoxy)-benzenesu...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108157(CHEMBL75139 | N-[2-[4-(4-Chloro-phenoxy)-benzenesu...)
Affinity DataIC50:  280nMAssay Description:In vitro selective inhibition against matrix metalloprotease-1 (MMP-1) using a fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108157(CHEMBL75139 | N-[2-[4-(4-Chloro-phenoxy)-benzenesu...)
Affinity DataIC50:  0.720nMAssay Description:In vitro selective inhibition against matrix metalloprotease-2 (MMP-2) using fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed