BDBM50108171 CHEMBL77874::N-Hydroxy-N-{3-hydroxy-2-hydroxymethyl-1-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonylmethyl]-propyl}-formamide

SMILES OCC(CO)C(CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)N(O)C=O

InChI Key InChIKey=WGXKBOQJZAHOOA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108171   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108171(CHEMBL77874 | N-Hydroxy-N-{3-hydroxy-2-hydroxymeth...)
Affinity DataIC50:  4.90nMAssay Description:In vitro selective inhibition against Matrix metalloprotease-9 (MMP-9) using fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108171(CHEMBL77874 | N-Hydroxy-N-{3-hydroxy-2-hydroxymeth...)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108171(CHEMBL77874 | N-Hydroxy-N-{3-hydroxy-2-hydroxymeth...)
Affinity DataIC50:  2.80nMAssay Description:In vitro selective inhibition against matrix metalloprotease-2 (MMP-2) using fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108171(CHEMBL77874 | N-Hydroxy-N-{3-hydroxy-2-hydroxymeth...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro selective inhibition against matrix metalloprotease-1 (MMP-1) using a fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed