BDBM50109051 CHEMBL330529::Methyl-[4-(6-methyl-benzothiazol-2-yl)-phenyl]-amine::US10137210, Example [N-methyl-11C]6-Me-BTA-1

SMILES CNc1ccc(cc1)-c1nc2ccc(C)cc2s1

InChI Key InChIKey=GGFYWXBSNMOKOK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50109051   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50109051(CHEMBL330529 | Methyl-[4-(6-methyl-benzothiazol-2-...)
Affinity DataKi:  10nMAssay Description:Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50109051(CHEMBL330529 | Methyl-[4-(6-methyl-benzothiazol-2-...)
Affinity DataKi:  20nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) fibrilsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50109051(CHEMBL330529 | Methyl-[4-(6-methyl-benzothiazol-2-...)
Affinity DataKi:  21nMAssay Description:Initial competitive binding studies using [3H]CG and synthetic Aβ(1-40) were conducted to determine if CG, ThS and ThT bound to the same site(s)...More data for this Ligand-Target Pair
In DepthDetails US Patent