BDBM50109527 CHEMBL3601120

SMILES OCCn1cc(Nc2ncc(Cl)c(NCc3cccc(NC(=O)C=C)c3)n2)cn1

InChI Key InChIKey=ALSJOMXUZWBKMB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109527   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109527(CHEMBL3601120)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of JAK3 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109527(CHEMBL3601120)
Affinity DataIC50:  140nMAssay Description:Inhibition of TYK2 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109527(CHEMBL3601120)
Affinity DataIC50:  143nMAssay Description:Inhibition of TTK (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109527(CHEMBL3601120)
Affinity DataIC50:  11nMAssay Description:Inhibition of JAK1 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109527(CHEMBL3601120)
Affinity DataIC50:  32nMAssay Description:Inhibition of JAK2 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed