BDBM50110225 3-[7-(4-Methyl-pyridin-2-ylamino)-heptanoylamino]-3-(3-nitro-phenyl)-propionic acid::CHEMBL417426

SMILES Cc1ccnc(NCCCCCCC(=O)NC(CC(O)=O)c2cccc(c2)[N+]([O-])=O)c1

InChI Key InChIKey=QXUZEPOJJWMXPE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50110225   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110225(3-[7-(4-Methyl-pyridin-2-ylamino)-heptanoylamino]-...)
Affinity DataIC50:  580nMAssay Description:Inhibition of fibrinogen binding to recombinant human platelet glycoprotein alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110225(3-[7-(4-Methyl-pyridin-2-ylamino)-heptanoylamino]-...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of integrin alpha-v/beta-5 mediated UCLAP-3 cell adhesion on vitronectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110225(3-[7-(4-Methyl-pyridin-2-ylamino)-heptanoylamino]-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of integrin alpha-v/beta-3 mediated M21 cell adhesion to vitronectin with monoclonal antibody P1F6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110225(3-[7-(4-Methyl-pyridin-2-ylamino)-heptanoylamino]-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110225(3-[7-(4-Methyl-pyridin-2-ylamino)-heptanoylamino]-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of integrin alpha-v/beta-6 mediated UCLAP-3 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110225(3-[7-(4-Methyl-pyridin-2-ylamino)-heptanoylamino]-...)
Affinity DataIC50:  53nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110225(3-[7-(4-Methyl-pyridin-2-ylamino)-heptanoylamino]-...)
Affinity DataIC50:  61nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed