BDBM50110229 3-({[2-(5-(4-methyl-pyridin-2-ylamino)-pentanoyl)hydrazino]carbonyl}amino)-3-(3,5-dichlorophenyl)propanoic acid::CHEMBL268056

SMILES Cc1ccnc(NCCCCC(=O)NNC(=O)NC(CC(O)=O)c2cc(Cl)cc(Cl)c2)c1

InChI Key InChIKey=VNWMBEFZMNRHEI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50110229   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110229(3-({[2-(5-(4-methyl-pyridin-2-ylamino)-pentanoyl)h...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of integrin alpha-v/beta-3 mediated M21 cell adhesion to vitronectin with monoclonal antibody P1F6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110229(3-({[2-(5-(4-methyl-pyridin-2-ylamino)-pentanoyl)h...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of fibrinogen binding to recombinant human platelet glycoprotein alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110229(3-({[2-(5-(4-methyl-pyridin-2-ylamino)-pentanoyl)h...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110229(3-({[2-(5-(4-methyl-pyridin-2-ylamino)-pentanoyl)h...)
Affinity DataIC50:  300nMAssay Description:Inhibition of integrin alpha-v/beta-6 mediated UCLAP-3 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110229(3-({[2-(5-(4-methyl-pyridin-2-ylamino)-pentanoyl)h...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of integrin alpha-v/beta-5 mediated UCLAP-3 cell adhesion on vitronectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110229(3-({[2-(5-(4-methyl-pyridin-2-ylamino)-pentanoyl)h...)
Affinity DataIC50:  64nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110229(3-({[2-(5-(4-methyl-pyridin-2-ylamino)-pentanoyl)h...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed