BDBM50110237 3-(3,5-Dichloro-phenyl)-4-{N'-[5-(4-methyl-pyridin-2-ylamino)-pentanoyl]-hydrazinocarbonyl}-butyric acid::CHEMBL9508

SMILES Cc1ccnc(NCCCCC(=O)NNC(=O)CC(CC(O)=O)c2cc(Cl)cc(Cl)c2)c1

InChI Key InChIKey=YQIZMAFWDNCDLY-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50110237   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110237(3-(3,5-Dichloro-phenyl)-4-{N'-[5-(4-methyl-pyridin...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of integrin alpha-v/beta-3 mediated M21 cell adhesion to vitronectin with monoclonal antibody P1F6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110237(3-(3,5-Dichloro-phenyl)-4-{N'-[5-(4-methyl-pyridin...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta5 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110237(3-(3,5-Dichloro-phenyl)-4-{N'-[5-(4-methyl-pyridin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of fibrinogen binding to recombinant human platelet glycoprotein alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110237(3-(3,5-Dichloro-phenyl)-4-{N'-[5-(4-methyl-pyridin...)
Affinity DataIC50:  6nMAssay Description:Inhibition of binding to alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110237(3-(3,5-Dichloro-phenyl)-4-{N'-[5-(4-methyl-pyridin...)
Affinity DataIC50:  44nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110237(3-(3,5-Dichloro-phenyl)-4-{N'-[5-(4-methyl-pyridin...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of integrin alpha-v/beta-6 mediated UCLAP-3 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110237(3-(3,5-Dichloro-phenyl)-4-{N'-[5-(4-methyl-pyridin...)
Affinity DataIC50:  6nMAssay Description:Inhibition of vitronectin binding to recombinant human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110237(3-(3,5-Dichloro-phenyl)-4-{N'-[5-(4-methyl-pyridin...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of integrin alpha-v/beta-5 mediated UCLAP-3 cell adhesion on vitronectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed