BDBM50110581 CHEMBL3605819

SMILES CC(C)(C)c1ccc(NC(=O)N2Cc3ccc(cc3C2)S(=O)(=O)Nc2ccc(F)cc2)cc1

InChI Key InChIKey=MKXWCSGELYEECH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110581   

Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50110581(CHEMBL3605819)
Affinity DataIC50:  594nMAssay Description:Inhibition of human recombinant MGAT2 assessed as reduction in enzyme-mediated deacylation of oleoyl-CoA incubated for 20 mins by CPM dye based fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-acylglycerol O-acyltransferase 2(Mus musculus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50110581(CHEMBL3605819)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of mouse recombinant MGAT2 assessed as reduction in enzyme-mediated deacylation of oleoyl-CoA incubated for 20 mins by CPM dye based fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed