BDBM50111577 CHEMBL3605055
SMILES C1CC(C1)c1cc(Nc2nc(Nc3ccc4[nH]cnc4c3)nc3ccccc23)n[nH]1
InChI Key InChIKey=DLCOOKRUECVLCI-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50111577
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of recombinant PDK1 (unknown origin) using PDK1tide substrate incubated for 7 minsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ULK2(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of SUMO-tagged ULK2 (unknown origin) kinase domain expressed in KRX cells using [32P]-gamma-ATP and myelin basic protein substrate incubat...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal SUMO-tagged ULK1 kinase domain (1 to 283 residues) (unknown origin) using MBP as substrate in presence of [32P]ATP after 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of ULK1 (unknown origin) by 32P-ATP radio active assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of SUMO-tagged ULK1 (unknown origin) kinase domain expressed in KRX cells using [32P]-gamma-ATP and myelin basic protein substrate incubat...More data for this Ligand-Target Pair