BDBM50111627 6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-benzothiazol-2-one::CHEMBL15955

SMILES Cn1c2ccc(CCN3CCN(Cc4ccccc4)CC3)cc2sc1=O

InChI Key InChIKey=KIBTUVSBDSDCNM-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50111627   

TargetSigma non-opioid intracellular receptor 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50111627(6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity for Sigma opioid receptor by displacement of [3H]-DTGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50111627(6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]- pyrilamine from rat brain membrane Histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50111627(6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-prazosin from rat cortex membrane 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50111627(6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-...)
Affinity DataKi:  500nMAssay Description:Compound was evaluated in vitro for its binding affinity towards Muscarinic acetylcholine receptor M1 by displacing [3H]- telenzepine from rat brain ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50111627(6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-...)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat hippocampus membrane 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50111627(6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]- raclopride from rat striatum Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50111627(6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-...)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]-ketanserin from rat cortex 5-HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed