BDBM50112136 CHEMBL3609864::US9464044, 39

SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CC1)NS(=O)(=O)c1ccccc1F)C(C3)C2

InChI Key InChIKey=CGPSAYFSIYKTQP-UVBRCKCBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112136   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112136(CHEMBL3609864 | US9464044, 39)
Affinity DataIC50:  24.7nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112136(CHEMBL3609864 | US9464044, 39)
Affinity DataIC50:  193nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112136(CHEMBL3609864 | US9464044, 39)
Affinity DataIC50:  25nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed