BDBM50112136 CHEMBL3609864::US9464044, 39
SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CC1)NS(=O)(=O)c1ccccc1F)C(C3)C2
InChI Key InChIKey=CGPSAYFSIYKTQP-UVBRCKCBSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50112136
Affinity DataIC50: 24.7nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University
Curated by ChEMBL
Incheon National University
Curated by ChEMBL
Affinity DataIC50: 193nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair