BDBM50112140 CHEMBL3609868::US9464044, 68

SMILES CC(C)(CNS(=O)(=O)c1ccccc1F)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O

InChI Key InChIKey=NJPOXQZWEHBUEC-PZVDWXJSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112140   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112140(CHEMBL3609868 | US9464044, 68)
Affinity DataIC50:  8.90nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112140(CHEMBL3609868 | US9464044, 68)
Affinity DataIC50:  204nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112140(CHEMBL3609868 | US9464044, 68)
Affinity DataIC50:  9nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed