BDBM50113349 CHEMBL457388
SMILES Fc1cccc(F)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
InChI Key InChIKey=CXBHMSHVCKEEGW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50113349
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin) by radiometric filter binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) by radiometric filter binding assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Shanghaitech University
Curated by ChEMBL
Shanghaitech University
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of CDK2/cyclin A2 (unknown origin) using FAM-labeled peptide and ATP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Shanghaitech University
Curated by ChEMBL
Shanghaitech University
Curated by ChEMBL
Affinity DataIC50: 594nMAssay Description:Inhibition of CDK1/cyclin B1 (unknown origin) using FAM-labeled peptide and ATP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Shanghaitech University
Curated by ChEMBL
Shanghaitech University
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of C-terminal His6-tagged human full length CDK2/N-terminal GST-tagged human full length Cyclin A using histone H1 and [gamma-32P]-ATP inc...More data for this Ligand-Target Pair