BDBM50113865 3-[6-(5-Carbamimidoyl-2,3-dihydroxy-phenoxy)-3,5-difluoro-4-methyl-pyridin-2-yloxy]-N,N-dimethyl-benzamide::CHEMBL82456

SMILES CN(C)C(=O)c1cccc(Oc2nc(Oc3cc(cc(O)c3O)C(N)=N)c(F)c(C)c2F)c1

InChI Key InChIKey=JDTMICVYIGEKMI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50113865   

TargetCoagulation factor X(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113865(3-[6-(5-Carbamimidoyl-2,3-dihydroxy-phenoxy)-3,5-d...)
Affinity DataKi:  23nMAssay Description:Inhibition of human Coagulation factor X was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113865(3-[6-(5-Carbamimidoyl-2,3-dihydroxy-phenoxy)-3,5-d...)
Affinity DataKi:  23nMAssay Description:Inhibitory constant against human coagulation factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50113865(3-[6-(5-Carbamimidoyl-2,3-dihydroxy-phenoxy)-3,5-d...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibitory constant against bovine trypsin for general specificity against serine proteasesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50113865(3-[6-(5-Carbamimidoyl-2,3-dihydroxy-phenoxy)-3,5-d...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibitory constant against human coagulation factor II (thrombin) for selectivity within coagulation cascadeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed