BDBM50114277 (S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-phenyl}-2-[4-(2-hydroxy-ethylamino)-6-methoxy-[1,3,5]triazin-2-ylamino]-propionic acid::CHEMBL41278

SMILES COc1nc(NCCO)nc(N[C@@H](Cc2ccc(NC(=O)c3c(Cl)cncc3Cl)cc2)C(O)=O)n1

InChI Key InChIKey=JHJOTWVMFJYVNC-HNNXBMFYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50114277   

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114277((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  320nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114277((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  7nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed