BDBM50114313 (S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-phenyl}-2-[2-(propane-1-sulfonyl)-pyrimidin-4-ylamino]-propionic acid::CHEMBL43571

SMILES CCCS(=O)(=O)c1nccc(N[C@@H](Cc2ccc(NC(=O)c3c(Cl)cncc3Cl)cc2)C(O)=O)n1

InChI Key InChIKey=HGRJPCSGYNCEGD-KRWDZBQOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50114313   

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114313((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  430nMAssay Description:Inhibition of very late antigen 4 from HL60 lysate in a protein-based ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114313((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  40nMAssay Description:Inhibition of very late antigen 4 expressed in Jurkat cell line, in a cell-based adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed