BDBM50115582 (Z)-4-[4-(3-Carboxy-3-hydroxy-acryloyl)-phenyl]-2-hydroxy-4-oxo-but-2-enoic acid::4-[4-(3-Carboxy-3-hydroxy-acryloyl)-phenyl]-2-hydroxy-4-oxo-but-2-enoic acid::CHEMBL108775

SMILES OC(=O)C(=O)CC(=O)c1ccc(cc1)C(=O)CC(=O)C(O)=O

InChI Key InChIKey=YNWWUDAZINNYPO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50115582   

TargetIntegrase(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50115582((Z)-4-[4-(3-Carboxy-3-hydroxy-acryloyl)-phenyl]-2-...)
Affinity DataIC50:  1.28E+3nMAssay Description:Strand transfer inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50115582((Z)-4-[4-(3-Carboxy-3-hydroxy-acryloyl)-phenyl]-2-...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibitory effect on 3'-processing(3'-P) of proviral DNA in an extracellular HIV-1 integrase assay in experiment 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50115582((Z)-4-[4-(3-Carboxy-3-hydroxy-acryloyl)-phenyl]-2-...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50115582((Z)-4-[4-(3-Carboxy-3-hydroxy-acryloyl)-phenyl]-2-...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibitory effect on 3'-processing(3'-P) of proviral DNA in an extracellular HIV-1 integrase assay in experiment 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed