BDBM50116680 CHEMBL3608523::US10053458, 56

SMILES COc1cc2CCCNCc2cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1

InChI Key InChIKey=CENVUXSKJJMKIU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50116680   

TargetInsulin receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50116680(CHEMBL3608523 | US10053458, 56)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of insulin receptor (unknown origin) by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50116680(CHEMBL3608523 | US10053458, 56)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of wild type ALK (unknown origin) by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

US Patent
LigandPNGBDBM50116680(CHEMBL3608523 | US10053458, 56)
Affinity DataIC50:  1nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50116680(CHEMBL3608523 | US10053458, 56)
Affinity DataIC50: <10nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50116680(CHEMBL3608523 | US10053458, 56)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed