BDBM50116687 CHEMBL3608645::US10053458, 55
SMILES COc1cc2CN(CCCc2cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1)C1COC1
InChI Key InChIKey=WCCLJJOUCIHEBN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50116687
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of wild type ALK (unknown origin) by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: <10nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair