BDBM50116940 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-isoxazol-3-ylmethyl}-pyrrolidin-2-one::CHEMBL309969

SMILES CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCC3=O)no2)CC1

InChI Key InChIKey=HUIUQPNWNWZOTQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50116940   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116940(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116940(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi:  66nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116940(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi:  2.99E+3nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed