BDBM50117203 4-[(7-Bromo-2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-N-pyridin-3-ylmethyl-benzamide::CB-30685::CHEMBL123446

SMILES Cc1nc2cc(Br)c(CN(CC#C)c3ccc(cc3)C(=O)NCc3cccnc3)cc2c(=O)[nH]1

InChI Key InChIKey=SHNBLWMBWXIKMR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117203   

TargetThymidylate synthase(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50117203(4-[(7-Bromo-2-methyl-4-oxo-3,4-dihydro-quinazolin-...)
Affinity DataIC50:  156nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50117203(4-[(7-Bromo-2-methyl-4-oxo-3,4-dihydro-quinazolin-...)
Affinity DataIC50:  156nMAssay Description:Growth inhibitory activity against mouse lymphoblastoid L1210TS cell line was determined as inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed