BDBM50117763 CHEMBL3613921::US9505753, 5u

SMILES Oc1nn(Cc2cccc3ccccc23)c(=O)[nH]c1=O

InChI Key InChIKey=DNIURSGRFSKVEF-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50117763   

TargetD-amino-acid oxidase(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50117763(CHEMBL3613921 | US9505753, 5u)
Affinity DataKi:  60nMAssay Description:Competitive inhibition of recombinant human DAAO expressed in HEK cells by double reciprocal plot analysis in presence of D-serineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50117763(CHEMBL3613921 | US9505753, 5u)
Affinity DataIC50:  50nMpH: 8.5 T: 2°CAssay Description:A reliable 96-well plate D-amino acid oxidase (DAAO) assay was developed based on previously published reports (J. Biol. Chem. 277: 27782 (2002)). Br...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50117763(CHEMBL3613921 | US9505753, 5u)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human DAAO expressed in HEK cells using D-serine as substrate assessed as formation of alpha-keto acid, ammonia, hydrogen p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed