BDBM50118781 3-(carboxyformamido)-5-(4-isobutylphenyl)thiophene-2-carboxylic acid::5-(4-Isobutyl-phenyl)-3-(oxalyl-amino)-thiophene-2-carboxylic acid::CHEMBL336435

SMILES CC(C)Cc1ccc(cc1)-c1cc(NC(=O)C(O)=O)c(s1)C(O)=O

InChI Key InChIKey=CBJMZUHIPHEMBH-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50118781   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118781(3-(carboxyformamido)-5-(4-isobutylphenyl)thiophene...)
Affinity DataKi:  1.29E+4nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118781(3-(carboxyformamido)-5-(4-isobutylphenyl)thiophene...)
Affinity DataKi:  1.30E+4nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118781(3-(carboxyformamido)-5-(4-isobutylphenyl)thiophene...)
Affinity DataKi:  1.30E+4nMAssay Description:Binding affinity to PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118781(3-(carboxyformamido)-5-(4-isobutylphenyl)thiophene...)
Affinity DataKi:  5.00E+4nMpH: 5.5Assay Description:Inhibitory effect against protein-tyrosine phosphatase Lar, using p-nitrophenyl phosphate as substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118781(3-(carboxyformamido)-5-(4-isobutylphenyl)thiophene...)
Affinity DataKi:  1.00E+5nMpH: 5.5Assay Description:Inhibitory effect against human protein-tyrosine phosphatase alpha (PTPalpha), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed