BDBM50118974 1-Acetyl-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL99072

SMILES COc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(C)=O

InChI Key InChIKey=OOCSYABQMHKMLM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118974   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118974(1-Acetyl-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tet...)
Affinity DataIC50:  1.40nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118974(1-Acetyl-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tet...)
Affinity DataIC50:  18nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50118974(1-Acetyl-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tet...)
Affinity DataIC50:  103nMAssay Description:Concentration required in vitro to inhibit TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118974(1-Acetyl-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tet...)
Affinity DataIC50:  1nMAssay Description:Concentration of the compound required in vitro to inhibit Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed