BDBM50120623 CHEMBL3618335

SMILES OC1CCN(CC1)c1ccc(cn1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1

InChI Key InChIKey=GFGHQEWOLXQMRD-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120623   

TargetMelanin-concentrating hormone receptor 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50120623(CHEMBL3618335)
Affinity DataKi:  12nMAssay Description:Displacement of [125I][Phe13,Tyr19]-MCH from human MCHR1 expressed in HEK293 cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50120623(CHEMBL3618335)
Affinity DataKi:  18nMAssay Description:Displacement of [125I][Phe13,Tyr19]-MCH from rat MCHR1 by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50120623(CHEMBL3618335)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells assessed as channel current by Q-patch electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50120623(CHEMBL3618335)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of human ERG by flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed