BDBM50120629 CHEMBL3618336

SMILES COc1cc(ccc1OCC(C)(C)O)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1

InChI Key InChIKey=GDEZUWDWHVVOHV-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50120629   

TargetMelanin-concentrating hormone receptor 1(Rat)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50120629(CHEMBL3618336)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I][Phe13,Tyr19]-MCH from rat MCHR1 by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50120629(CHEMBL3618336)
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I][Phe13,Tyr19]-MCH from human MCHR1 expressed in HEK293 cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50120629(CHEMBL3618336)
Affinity DataIC50:  44nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-induced Ca2+ influx for 120 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed