BDBM50121510 CHEMBL150908::N*1*-[1-Benzyl-3-(2-tert-butylcarbamoyl-phenylamino)-2-hydroxy-propyl]-2-[(quinoline-2-carbonyl)-amino]-succinamide

SMILES CC(C)(C)NC(=O)c1ccccc1NC[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1

InChI Key InChIKey=NPWARPHZHOFXPU-DTXPUJKBSA-N

Data  2 KI  2 Kd  1 Koff  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50121510   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50121510(CHEMBL150908 | N*1*-[1-Benzyl-3-(2-tert-butylcarba...)
Affinity DataKi:  55nM Kd:  366nM Koff:  1.08E+6s-1Assay Description:Association rate constant for the interaction between inhibitor and HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50121510(CHEMBL150908 | N*1*-[1-Benzyl-3-(2-tert-butylcarba...)
Affinity DataKi:  55nMAssay Description:Inhibition constant for human immunodeficiency virus type 1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50121510(CHEMBL150908 | N*1*-[1-Benzyl-3-(2-tert-butylcarba...)
Affinity DataKd:  366nMAssay Description:Binding affinity for human immunodeficiency virus type 1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50121510(CHEMBL150908 | N*1*-[1-Benzyl-3-(2-tert-butylcarba...)
Affinity DataKon:  0.373M-1s-1Assay Description:Association rate constant for the interaction between inhibitor and HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed