BDBM50121736 (R,S)Piperidin-2-yl-(4-pyridin-3-ylmethyl-piperazin-1-yl)-methanone::CHEMBL6346::SCR-01020::SCR01020

SMILES O=C(C1CCCCN1)N1CCN(Cc2cccnc2)CC1

InChI Key InChIKey=SHVTUGFWWFPRNZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121736   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50121736((R,S)Piperidin-2-yl-(4-pyridin-3-ylmethyl-piperazi...)
Affinity DataKi:  5.48E+4nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50121736((R,S)Piperidin-2-yl-(4-pyridin-3-ylmethyl-piperazi...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha-7 neuronal nicotonic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed