BDBM50121955 4-Phenyl-pyridine::CHEMBL109074::US11634391, Compound 233

SMILES c1ccc(cc1)-c1ccncc1

InChI Key InChIKey=JVZRCNQLWOELDU-UHFFFAOYSA-N

Data  2 IC50  4 Kd

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50121955   

TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121955(4-Phenyl-pyridine | CHEMBL109074 | US11634391, Com...)
Affinity DataKd:  1.70E+5nMAssay Description:Binding to stromelysin (MMP-3) in the presence of acetohydroxamic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121955(4-Phenyl-pyridine | CHEMBL109074 | US11634391, Com...)
Affinity DataKd:  9.00E+5nMAssay Description:Binding to stromelysin (MMP-3) in the presence of 1-NapthohydroxamateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
Ucl Business

US Patent
LigandPNGBDBM50121955(4-Phenyl-pyridine | CHEMBL109074 | US11634391, Com...)
Affinity DataIC50:  1.74E+3nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetBeta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50121955(4-Phenyl-pyridine | CHEMBL109074 | US11634391, Com...)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to native signal deficient and TEV cleavage site containing His-tagged Klebsiella pneumoniae OXA-48 expressed in Escherichia coli as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50121955(4-Phenyl-pyridine | CHEMBL109074 | US11634391, Com...)
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of native signal containing Klebsiella pneumoniae OXA-48 using nitrocefin substrate pre-incubated for 5 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeregrin(Human)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50121955(4-Phenyl-pyridine | CHEMBL109074 | US11634391, Com...)
Affinity DataKd: >2.00E+5nMAssay Description:Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assayMore data for this Ligand-Target Pair