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BDBM50122071 Ac-His-D-Phe-Arg-His-NH2::CHEMBL350012

SMILES: CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cnc[nH]1)C(N)=O

InChI Key: InChIKey=MRXXHRTVXCNCKC-KIHHCIJBSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50122071   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Mus musculus)
BDBM50122071
PNG
(Ac-His-D-Phe-Arg-His-NH2 | CHEMBL350012)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cnc[nH]1)C(N)=O
Show InChI InChI=1S/C29H40N12O5/c1-17(42)38-24(12-20-14-34-16-37-20)28(46)41-23(10-18-6-3-2-4-7-18)27(45)39-21(8-5-9-35-29(31)32)26(44)40-22(25(30)43)11-19-13-33-15-36-19/h2-4,6-7,13-16,21-24H,5,8-12H2,1H3,(H2,30,43)(H,33,36)(H,34,37)(H,38,42)(H,39,45)(H,40,44)(H,41,46)(H4,31,32,35)/t21-,22+,23-,24-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.76E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells


J Med Chem 45: 5736-44 (2002)


Article DOI: 10.1021/jm020296e
BindingDB Entry DOI: 10.7270/Q2Q2410R
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50122071
PNG
(Ac-His-D-Phe-Arg-His-NH2 | CHEMBL350012)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cnc[nH]1)C(N)=O
Show InChI InChI=1S/C29H40N12O5/c1-17(42)38-24(12-20-14-34-16-37-20)28(46)41-23(10-18-6-3-2-4-7-18)27(45)39-21(8-5-9-35-29(31)32)26(44)40-22(25(30)43)11-19-13-33-15-36-19/h2-4,6-7,13-16,21-24H,5,8-12H2,1H3,(H2,30,43)(H,33,36)(H,34,37)(H,38,42)(H,39,45)(H,40,44)(H,41,46)(H4,31,32,35)/t21-,22+,23-,24-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.80E+3n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells


J Med Chem 45: 5736-44 (2002)


Article DOI: 10.1021/jm020296e
BindingDB Entry DOI: 10.7270/Q2Q2410R
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50122071
PNG
(Ac-His-D-Phe-Arg-His-NH2 | CHEMBL350012)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cnc[nH]1)C(N)=O
Show InChI InChI=1S/C29H40N12O5/c1-17(42)38-24(12-20-14-34-16-37-20)28(46)41-23(10-18-6-3-2-4-7-18)27(45)39-21(8-5-9-35-29(31)32)26(44)40-22(25(30)43)11-19-13-33-15-36-19/h2-4,6-7,13-16,21-24H,5,8-12H2,1H3,(H2,30,43)(H,33,36)(H,34,37)(H,38,42)(H,39,45)(H,40,44)(H,41,46)(H4,31,32,35)/t21-,22+,23-,24-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells


J Med Chem 45: 5736-44 (2002)


Article DOI: 10.1021/jm020296e
BindingDB Entry DOI: 10.7270/Q2Q2410R
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50122071
PNG
(Ac-His-D-Phe-Arg-His-NH2 | CHEMBL350012)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cnc[nH]1)C(N)=O
Show InChI InChI=1S/C29H40N12O5/c1-17(42)38-24(12-20-14-34-16-37-20)28(46)41-23(10-18-6-3-2-4-7-18)27(45)39-21(8-5-9-35-29(31)32)26(44)40-22(25(30)43)11-19-13-33-15-36-19/h2-4,6-7,13-16,21-24H,5,8-12H2,1H3,(H2,30,43)(H,33,36)(H,34,37)(H,38,42)(H,39,45)(H,40,44)(H,41,46)(H4,31,32,35)/t21-,22+,23-,24-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.60E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells


J Med Chem 45: 5736-44 (2002)


Article DOI: 10.1021/jm020296e
BindingDB Entry DOI: 10.7270/Q2Q2410R
More data for this
Ligand-Target Pair