BDBM50122322 CHEMBL3622147

SMILES CCn1c(cc2c1nc(Nc1nc(C)n(C)n1)c1ncn(C)c21)C(=O)N(C1CC1)C1CC1

InChI Key InChIKey=DECMNAIMXFYLFZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50122322   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50122322(CHEMBL3622147)
Affinity DataIC50:  33nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) using 5-FAM-KKKKEEIYFFFG-OH substrate and ATP incubated for 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50122322(CHEMBL3622147)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using 5-FAM-KKKKEEIYFFFG-OH substrate and ATP incubated for 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50122322(CHEMBL3622147)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using 5-FAM-KKKKEEIYFFFG-OH substrate and ATP incubated for 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed