BDBM50123114 2-[1-(4-Diethylamino-phenyl)-meth-(E)-ylidene]-6,7-dihydroxy-benzofuran-3-one::CHEMBL334500

SMILES CCN(CC)c1ccc(\C=C2\Oc3c(ccc(O)c3O)C2=O)cc1

InChI Key InChIKey=FIJOFUUQGBYKPA-LFIBNONCSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123114   

Target3-phosphoshikimate 1-carboxyvinyltransferase(Escherichia coli (strain K12))
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123114(2-[1-(4-Diethylamino-phenyl)-meth-(E)-ylidene]-6,7...)
Affinity DataKi:  650nMAssay Description:Competitive inhibitory activity of the compound was determined with respect to EPSP (5-enolpyruvylshikimate- 3-phosphate) synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123114(2-[1-(4-Diethylamino-phenyl)-meth-(E)-ylidene]-6,7...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed