BDBM50123785 4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(5-oxy-1H-pyrrolo[3,2-c]pyridin-2-ylmethyl)-piperazin-2-one::CHEMBL161432

SMILES [O-][n+]1ccc2[nH]c(CN3CCN(CC3=O)S(=O)(=O)c3cc4ccc(Cl)cc4s3)cc2c1

InChI Key InChIKey=LATAMKXJDNPECS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50123785   

TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123785(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(5-oxy...)
Affinity DataKi:  38nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123785(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(5-oxy...)
Affinity DataKi: >2.90E+3nMAssay Description:Binding affinity towards trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123785(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(5-oxy...)
Affinity DataKi: >3.90E+3nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed