BDBM50123967 3-[4-(Biphenyl-4-ylsulfamoyl)-phenyl]-N-hydroxy-acrylamide::CHEMBL434466::US8796330, 162
SMILES ONC(=O)\C=C\c1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1ccccc1
InChI Key InChIKey=TWAKWKHDTZWUMO-OVCLIPMQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50123967
Affinity DataIC50: 40nMT: 2°CAssay Description:For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of acetylation of histone-4 in human T-24 cancer cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration against human Histone deacetylase 1More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibitory activity on partially purified recombinant human Histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair