BDBM50123977 3-[4-(5-Dimethylamino-naphthalene-1-sulfonylamino)-phenyl]-N-hydroxy-acrylamide::CHEMBL166496::US8796330, 97

SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(\C=C\C(=O)NO)cc1

InChI Key InChIKey=DGVBTGGYDRMFCM-SDNWHVSQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123977   

TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50123977(3-[4-(5-Dimethylamino-naphthalene-1-sulfonylamino)...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity on partially purified recombinant human Histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50123977(3-[4-(5-Dimethylamino-naphthalene-1-sulfonylamino)...)
Affinity DataIC50:  280nMT: 2°CAssay Description:For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...More data for this Ligand-Target Pair
In DepthDetails US Patent