BDBM50124141 CHEMBL3622805

SMILES CN[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C[Si](C)(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O

InChI Key InChIKey=JXXKKBSAIYYKNT-JNRWAQIZSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50124141   

TargetNeurotensin receptor type 2(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50124141(CHEMBL3622805)
Affinity DataIC50:  30nMAssay Description:Displacement of [125I]-Tyr3-NT from human NTS2 receptor expressed in 1321N1 cell membranes incubated for 30 mins by gamma-counting based competitive ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50124141(CHEMBL3622805)
Affinity DataEC50:  204nMAssay Description:Agonist activity at human NTS1 receptor expressed in CHOK1 cells co-expressing Galphaq-RlucII(121)/Gbeta1/GFP10-Ggamma1 assessed as Galpha-q stimulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50124141(CHEMBL3622805)
Affinity DataIC50:  246nMAssay Description:Displacement of [125I]-Tyr3-NT from human NTS1 receptor expressed in CHOK1 cell membranes incubated for 30 mins by gamma-counting based competitive r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Rattus norvegicus)
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50124141(CHEMBL3622805)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human NTS1 in Sprague-Dawley rat ileum assessed as inhibition of carbachol-induced contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50124141(CHEMBL3622805)
Affinity DataEC50:  4.20nMAssay Description:Agonist activity at human NTS1 receptor expressed in CHOK1 cells co-expressing hNTS1-GFP10/RlucII-beta-arrestin 2 assessed as beta-arrestin2 recruitm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed