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BDBM50124652 CHEMBL3622905

SMILES: Cc1c(Cl)nc(nc1Cl)C1CC1

InChI Key: InChIKey=AEKXEKPMZIZYLD-UHFFFAOYSA-N

Data: 1 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124652   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50124652
PNG
(CHEMBL3622905)
Show SMILES Cc1c(Cl)nc(nc1Cl)C1CC1
Show InChI InChI=1S/C8H8Cl2N2/c1-4-6(9)11-8(5-2-3-5)12-7(4)10/h5H,2-3H2,1H3
PDB
MMDB

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PC cid
PC sid
PDB
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Similars

PDB
PubMed
8.70E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human PDE10A2 transfected in AD293 cells by IMAP FP assay


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)