BDBM50125228 (S)-2-(2-Bromo-benzoylamino)-3-(1H-indol-3-yl)-propionic acid::CHEMBL268669

SMILES OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccccc1Br

InChI Key InChIKey=PYLJGABTKOZRCY-INIZCTEOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125228   

TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50125228((S)-2-(2-Bromo-benzoylamino)-3-(1H-indol-3-yl)-pro...)
Affinity DataIC50:  1.72E+3nMAssay Description:Inhibition of LFA1/ICAM1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50125228((S)-2-(2-Bromo-benzoylamino)-3-(1H-indol-3-yl)-pro...)
Affinity DataIC50:  1.72E+3nMAssay Description:Inhibitory activity against association of LFA-1 with intercellular adhesion molecule 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50125228((S)-2-(2-Bromo-benzoylamino)-3-(1H-indol-3-yl)-pro...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro inhibitory potency for preventing ET-1 induced constriction of rat aortic rings (ETA receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed