BDBM50125489 (6S,8R)-1-Chloro-8-(4-methoxy-benzyl)-4-oxo-3-(3-trifluoromethyl-benzylamino)-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic acid [(R)-1-((R)-2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0*2,6*]dec-4-yl)-but-3-enyl]-amide::CHEMBL15861

SMILES COc1ccc(C[C@@H]2C[C@@H](C(=O)N[C@@H](CC=C)B3OC4CC5CC(C5(C)C)[C@@]4(C)O3)n3c2c(Cl)nc(NCc2cccc(c2)C(F)(F)F)c3=O)cc1

InChI Key InChIKey=NUDRCFFRFVAZHB-DTDIWWSVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125489   

TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125489((6S,8R)-1-Chloro-8-(4-methoxy-benzyl)-4-oxo-3-(3-t...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against HCV NS3 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed